The Shuttle was poorly designed for safety and civilian missions. It was also expensive for what we used it for. The Shuttle was supposed to be retired in the early 90’s. The ISS delays kept it going.
In the next 3 years we’re going to have more crewed capsules and rockets than we’ll know what to do with. They’ll all be safer, far more economical and better suited for their missions than the Shuttle.
I think I read that the first “populated”(can’t say ‘manned’ anymore due to PC rulings and regs) launch has been pushed to 2021 now. Also, Sierra Nevada has gotten a contract for their mini-shuttle to fly some missions after all.
http://spacenews.com/europe-to-invest-in-sierra-nevadas-dream-chaser-cargo-vehicle/
Then there’s this about Orion:
http://spacenews.com/lockheed-says-orion-still-on-schedule-for-2018-mission/