It would be savage...and there are a lot of people between to get to him....agreed...
Drug cartels makes billions of dollars every year...money is no object to them...look at the money that is carted out of America into Mexico by them every day across our border...
That said, if El Chapo wanted to arrange a hit, he would know who to contact.
And considering that Trump is going to damage El Chapo's business by building a wall, he might be motivated to take action before the election.