Maybe if they pick too big a gun for them, but then again, its not actually in your hand all day.
The only thing I had to consider was the Butt size, then as Arthur set into the hands I had to switch to a Taurus Ultra Lite Revolver, when I could no longer rack my Bersa .38.
Now I have to worry about kick back as I developed Osteoporosis as well as Osteo Arthritis in my shooting Right hand.
It wasn’t the weight of the gun, as I can shoot the 9mm Ruger, it’s just that the Butt is to big for my smaller hands to wrap around it well.