It is a specific case of a generality that we should not be blaming the material world for matters that are within the realm of God and demons.
(Which also makes the War On Drugs, in its present form [rather than a War on Abuse], look foolish.)
They manifest physically. When they do, we take the physical sword the Lord commanded us to own (Luke 22:36) and stop them.
Today we choose the modern equivalent — a firearm.
There is a time for peace and a time for war — everything in its season. We use spiritual weapons to bring the gospel to a dying world. When a armed sociopath tries to kill us, it’s time to deliver effective fire.