Ironically, Rockefeller died of a heart attack in 1979 in "intimate circumstances" in the company of a young woman who worked for him.
GOP primary voters have a long history of being very socially conservative and this applies especially to presidential candidates. When it was learned that Rocky was divorcing his wife for a much younger trophy this did not play well with most GOP primary voters. RR too was divorced and remarried. However, it was his first wife, Jane Wyman, who left him. And when RR remarried it was to someone who was at least much closer to his own age, not a trophy wife.