Here's the deal with "original intent" - It doesn't matter what your or I think. Asking what I think about it is just a distraction to keep you from having to actually provide any answers.
What matters is what the people who wrote and ratified the Constitution thought.
And I'm pretty sure they would have thought that transshipping dangerous narcotics across the border to hurt or injure our citizens would be considered a criminal act if done by individuals, and an act of war if done by a nation state.
That is axiomatic. You just don't like it because it disables your "NO LEGAL AUTHORITY TO INTERDICT DRUGS!!!!" assertion.