It is relatively safe to handle the leafless woody parts after it's been 20 below a few times, but the stuff is incredibly poisonous, even the chips or sawdust, and the smoke is downright dangerous if you're thinking of the napalm method. Not for the faint of heart. Rainy day, dawn, no wind, and you didn't hear it from me.
The local Indians had a way of desensitizing themselves to PI, but I would never risk it, and if I told you the secret, I would have to ... you know the rest!
If you do get a dose, go to the beach and stay under salt water until it goes away. Might take a week in the Bahamas!
I finally got the PI out of the yard here at the house but when I go to the ranch I don’t get out of the p/u. I can spot it from 30 feet away. I know not to burn it!