[Calvin Locke]

One breast cancer drug that was in a double blind study had early results were so promising, at least for what it was intended, that they came to the conclusion that it was unethical to continue with a placebo as part of the trials.

I have a relative that was in a trial for some drug for a while. He was taking the drug to begin with, before being asked to participate in the trial.

He knew he had the placebo in the trial because it didn't cut/break in half the same way as the real stuff.

[Smokin' Joe]

One breast cancer drug that was in a double blind study had early results were so promising, at least for what it was intended, that they came to the conclusion that it was unethical to continue with a placebo as part of the trials.

Some of science has become a process of splitting statistical hairs to the degree that the inherently obvious is not allowed for in the construction of studies.

Given a large base of people who have not received the drugs or vaccines already, even with questions about the record keeping, anything which gives patients a significant edge should be readily obvious, improving survival rates by a readily recognizable factor.