From wikipedia:
“The 2006 Michigan State vs. Northwestern football game featured one of the biggest comebacks in NCAA history. The Spartans (Michigan State) rallied to score 38 unanswered points to beat the Wildcats (Northwestern) 41–38 after falling behind 38–3 with 9:54 left in the 3rd quarter.”
Ask Michigan State whether there should be a “mercy rule” or whether games should end at a certain score.
Or ask the '93 Buffalo Bills, they were behind to the Houston Oilers 35-3 in the 3rd quarter o their playoff game.