If it's just a few hours I can put up with pretty much anything. My recent trip was 7 hours from JFK to Amsterdam, and then 11 hours from there to Zambia. I did business class for those segments... makes a huge difference.
I imagine so.
I used to have to fly from Maryland to CA for work and being cramps in a cattle car for three hours is painful.
I like to be able to use my laptop and in some of those seats its against my stomach.