It all depends which hemisphere of the brain dominates. Physics, I guess, are old hat by now, while economics and finance are still mysterious (and tend to engender conservative thinking). Medicine seems to be an all-time favorite, employing a balanced use of both hemispheres.
Or maybe the old theory of Arthur Koestler, that the marriage of Talmudic scholars sons to bankers daughters produced a good lot of brainy kids, when were then caught up in the new math and physics of the 19th and 20th century, as a new spiritual quest. Or maybe it is that some guys like Dick Feynman are just intrigued by puzzles. He was also a great safecracker! At Los Alamos, no combination lock was safe from his fingers.