To: steve86
I just found out yesterday that Loperamide is a form of demerol that doesn’t cross the blood/brain barrier, but does effect the opioid receptors in the gut. That’s how it stops constipation.
From what I read, addicts are using it to ease the symptoms of withdrawal in an effort to get off drugs.
89 posted on
10/26/2013 3:53:01 PM PDT by
Marie
(When are they going to take back Obama's peace prize?)
To: Marie
Thats how it stops constipation. You have that backwards.
93 posted on
10/26/2013 4:01:45 PM PDT by
steve86
(Some things aren't really true but you wouldn't be half surprised if they were.)
To: Marie
Thats how it stops constipation. I think you misspoke. Loperamide is for stopping diarrhea........ Loperamide is an opioid-receptor agonist and acts on the μ-opioid receptors in the myenteric plexus of the large intestine; by itself it does not affect the central nervous system. It works similarly to morphine, by decreasing the activity of the myenteric plexus, which in turn decreases the tone of the longitudinal and circular smooth muscles of the intestinal wall.[5][6] This increases the amount of time substances stay in the intestine, allowing for more water to be absorbed out of the fecal matter. Loperamide also decreases colonic mass movements and suppresses the gastrocolic reflex.[
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