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To: EDINVA

Dupilumab is a monoclonal antibody. I don’t think it will be cheap.

From the 2nd link:

“Rather, it shows that dupilumab is able to substitute inhaled glucocorticoids and LABAs(long acting beta agonists) in a specific subgroup of patients with asthma, but whether or not this drug has added value over treatment with inhaled glucocorticoids and LABAs in patients with moderate-to-severe asthma remains to be established. This is both clinically and biologically important, because inhaled glucocorticoids and LABAs target type 2 helper T cell (Th2) pathways, so we may need to look elsewhere to find the needed treatments for difficult-to-treat asthma.”

Glucocorticoids are steroids. You don’t want to use them unless you must, even the inhaled ones. I’m a doc. Good luck!


4 posted on 05/22/2013 10:50:18 PM PDT by neverdem (Register pressure cookers! /s)
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To: neverdem

I use Serevent to control my asthma, and nothing ticked me off more than when they took the aerosolized version off the market in order to “save the ozone layer.” I went from being asthma-free to “somewhat” asthma-free.

So far as this new treatment is concerned, I’d be leery about it until some long-term studies have been done.


6 posted on 05/23/2013 12:08:59 AM PDT by Mr Ramsbotham (Laws against sodomy are honored in the breech.)
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