[corkoman]

Try again - but this time stick to the issue - show us any controlled clinical study demonstrating a significant effect from any of the antioxidants.

[Neoliberalnot]

Go to pubmed and look for yourself. I am not here to do your literature search for you. I do understand chemical reactions and living systems mechanisms. Ascorbate usually acts as an antioxidant when doses are reasonable. It typically reacts with potent reactive oxygen species, such as the hydroxyl radical formed from hydrogen peroxide. Such radicals are damaging to animals and plants at the molecular level due to their possible interaction with nucleic acids, proteins, and lipids. Sometimes these radicals initiate chain reactions. Ascorbate can terminate these chain radical reactions by electron transfer. Ascorbic acid is special because it can transfer a single electron, owing to the stability of its own radical ion called "semidehydroascorbate", dehydroascorbate. The net reaction is: RO • + C6H7O6- → ROH + C6H6O6• - On the other hand, excessive or toxic doses of Vit C can actually initiate free radical formation and damage. The mega dose proponents don't want to hear this, but every substance is toxic and just a matter of dose.