Two words, ‘opium dens’.
“From 1776 to 1914, drugs were mostly legal on a federal and local level.”
Please review the history of Opium Dens in the US and laws passed in response to them with respect to the statement quoted above.
Also available-right along with opium-cultivated and even traded since long before the 19th century-coca, ergot and other grain molds, peyote, psilosyben(sp), and of course, marijuana-organic drugs were used thousands of years ago, right along with beer, wine and uisge/whisky-ancient humankind was apparently not innocent of intoxication of any sort...