“What you are describing is called nullification and is a strong assertion of state’s rights doctrine. There is a clear potential for a Constitutional crisis unmatched since 1860 emerging here.”
Not really, because only a tiny minority would go along with that theory, so it will never get far.
Nobody considers the fact that most people are simply not thinking this way. Few Americans even understand basic federalism let alone would support a pre-CivilWar view of federal-state relations. So it remains a pipedream.
It’s kind of like these crazy ideas for a constitutional convention. Do people advocating it realize that a majority of Americans voted for Obama in 2008? Do they really want a new constitution written by a convention that is 50% controlled by Obama-types? The odds of getting an improved constitution out of that is ... nil.