That has been tried. It didn’t work out very well.
What if the concept of “the consent of the governed” was finally rendered moot at Appomattox in 1865?
What we have today is the inevitable result.
The 2nd Amendment allowed for CW-I. The next “CW” would look more like Iraq or Afghanistan. That worked out well.
When at first you don't succeed, try, try again.
Do you think that the American Revolution worked out smoothly, with no slip-ups, no enemy victories, no casualties? The obvious answer is "no" - but that didn't prevent the Founding Generation from regrouping, licking its collective wounds and trying again and again until the Brits tired of fighting us and left.
To those on this thread who think that the fact that so many are dependent upon and supportive of the feds means an automatic defeat: think again. First off, if they're so dependent, then by definition they're sheep. Second, the American Revolution was not supported by all of the people - roughly 1/3 of the population were Loyalists and not only didn't help, but actively hindered the Revolution and cooperated with the British tyrants...and yet it is they who left for Canada or England when the bullets stopped flying. It is good to be aware of and realistic about what resources your enemy has at his disposal, but it is unwise to think that there is no way to defeat Leviathan...just ask the cave-dwellers in Afghanistan, who have defeated the 2 most powerful empires known to human history in a single generation.