It does more harm than good. I live in a rural area where "illicit" drugs would be much harder to come by if they were decriminalized or legalized. The use of really dangerous substances thus is far higher than it would be absent drug prohibition. The government can prohibit a substance but it can't prohibit profit motive or repeal self-interest.
Moonshining has been prohibited by the Feds for more than 200 years. I'd say there hasn't been any moonshine produced hereabouts since . . . um . . . this morning. Likewise, there hasn't been any marijuana harvested in this vicinity since, oh, August or September. IMHO, prohibition laws ultimately make a mockery of government.
That’s funny, I’ve never seen illegal moonshine once, anywhere. I sure see a lot of beer and wine though all over. Seems you disproved your own point by bringing that up. Oops.