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To: Wacka; allmendream

What about animals? And people for example?

I’ve yet to find any information that indicates that a change in the number of chromosomes produces or ever has produced a beneficial change. At best, it might be neutral, if there are other factors involved.

http://ghr.nlm.nih.gov/handbook/mutationsanddisorders/chromosomalconditions
http://www.genetics.com.au/pdf/factsheets/fs06.pdf

Are you saying then that this is the case only for humans? That it is not representative across the board in the animal kingdom? Do changes in the number of chromosomes have no effect or a beneficial one in animals only but not humans?

Examples please.


103 posted on 12/03/2009 12:22:45 PM PST by metmom (Welfare was never meant to be a career choice.)
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To: metmom
Who said anything about it being beneficial?

Previously your statement was that it would always be deleterious; as in... “I have yet to be informed of any changes in the number of chromosomes which has not had a deleterious effect on the individual in which it occurs.”

Now it has to be a beneficial change? Why?

And why do you think there would be a difference in the general genetic principle I outlined between humans and non-human animals? Are you ignorant enough to think genetics works differently in humans?

http://www.springerlink.com/content/x070p137m7114334/

Here is a study on a population of grasshoppers that seem MORE subject to chromosomal fusion. The grasshoppers lived and reproduced just fine with two or more of their chromosomes packaged together rather than separate and they had an increased rate of chromosomal fusion that that observed in the natural population (for those of you in Rio Linda, that means that this DOES happen in the natural population, just not as frequently).

Is the underlying concept REALLY that hard for you to understand such that I have to repeat it to you every couple of months or so?

Chromosomal abnormalities that change gene copy number lead to problems because you have either three copies of something you really need to only have two of, or only one copy of something you really need two copies of.

If two people each have two copies of every gene they need two copies of- but one has them packaged in 46 different packages, and the other in 45 different packages - do you think somehow in someway it is going to cause the same problems as having only one copy or having three copies of a gene?

107 posted on 12/03/2009 12:44:45 PM PST by allmendream (Wealth is EARNED not distributed, so how could it be RE-distributed?)
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To: metmom
One of the several times I have explained this to you in the past; this from October of 2008. And yet you still trot out the “nobody has ever explained to me how...” line. Still insisting that it just HAS to be a problem.

Why are you so resistant to learning even the most simple and basic things about genetics. Years of discussion and not one bit of actual information has penetrated. Now that seems pretty dense.

http://freerepublic.com/focus/chat/2108022/posts?page=707

Chromosomal fusion would not lead to aneuploidy problems.
Aneuploidy like Downs syndrome, Klinefelters, etc are either a loss of an entire chromosome or the gain of an extra copy of a chromosome.

Chromosomal fusion is just a rearrangement of the same genes in 23 packages (x2) rather than 24 packages (x2).

No muss no fuss.

There are even the relics of an unused centromere on Chromosome two and telomeres where the fused chromosomes used to end.

Just a bit of research would answer your questions.

113 posted on 12/03/2009 12:58:57 PM PST by allmendream (Wealth is EARNED not distributed, so how could it be RE-distributed?)
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