Yes and I should have been more careful. What I meant was that along the frontier interface, the natives were stone age and either fought and died as stone age people or, they more or less integrated with Europeans.
They really didn’t have much interface time. Unlike the Spaniards, the English brought their women with them, and the insatiable demand for land meant that the indians were pushed out of the way. The Iroquois had the best chance of all , since they were highly organized, but then they made the mistake of siding with the British against the Continentals. My guess is that if they had not, then upstate New York would be more like Oklahoma.
As for fighting a dying like “stone age people,” the Sioux for instance, adapted rather quickly. They took up the horse and the rifle quite quickly as they moved out onto the plains to living by harvesting the great herds. As they have investigated the Little Big Horn battle field, researchers have discovered why Custer got mowed down: the 2000 indian warriors they faced had a lot of guns, a LOT of guns. Years later Sitting Bull lead a hunting expedition and killed thousands of buffalo. Don;t do that with lances. Those guys could shoot.