“Hunting alone likely won’t do it”
...oh yes it will! ....put a financial reward on the snakes and hunters will wipe them out....I’ve seen market forces almost eradicate alligators in my lifetime...only to see them bounce back when protected....if the money is right, guys will hunt pythons to extinction.
Exactlty, put a bounty on them like they did in the western US with wolves, etc.
Problem solved.
OR even better spread the story that certain Florida Pythons parts are an aphrodisiac or improve male stamina and sell hunting trips to wealthy Asians.