Beats me, why don't you look it up for yourself?
I just know how the stuff is made and what it's used for. It's used in hormone replacement therapy. And in birth control pills as well. So there you go, pills, and no doubt there are creams, and trans-dermal patches as well. probably even injections too. Look it up.
Well....smarty, maybe you should do a little research yourself.....I’ve done it. And, I know the delivery method and dose matter a whole he** of a lot....