[JOAT]

Thus the of the cancers that grow and survive within the body long enough to be detected; around 50% have already shut off the mechanism whereby the cell would be instructed to kill itself.

K.

You're still describing the effect, not the cause.

Now instruct us (who are less likely to die from cancer) about the WHY question I asked. Why is p53 mutating and allowing cancerous cells to propagate?

It's easy to point to a breakdown in the defenses, but why are the defense mechanisms of the immune system breaking down in the first place and allowing the cancerous cells to live?

If you have the answer to that, you should stop wasting your time lecturing noobs on a political board and get down to the CDC with your findings!

[allmendream]

The cause of around 50% of cancers having a non functional p53 gene is that those that do not are more likely to have been eliminated.

The cause of around 50% of people admitted to MIT having SAT’s above 1400 is that those without high test scores are eliminated from consideration.

Why is p53 mutating? Because mutation can and does happen.

Why are those cancers that grow and survive more likely to have p53 mutated? Because a functional p53 gene kills growing cancer cells.

p53 is not part of the immune system. The gene is expressed in every cell line.