What's wrong with materialism? If somebody asks me for directions, I give them materialist directions. I don't tell them to close their eyes and wait for God to tell them, otherwise they would be waiting forever. That doesn't mean God doesn't exist, it just means he doesn't work that way.
Likewise, we use materialism to explain biology. If we waited for God to poof up living things out of nothing, we'd be waiting forever. He doesn't work that way.