[Clint N. Suhks]

I recommend head shots. [deer]

Never heard that before. That's a pretty small target compared to the heart.

[vacuumbob]

Head shot is the best. Draw a line from one ear to the opposite eye, and again the other way. where the lines cross is the spot

[Roccus]

That's a pretty small target compared to the heart.

Not really. Deer hearts ain't all that big. Head is a smaller target than what is often called the "kill zone", but that "zone" also encompasses the lungs which are most likely to be hit. Hit 'em in the lungs and they will die.....after they jump and run for a bit spreading the adrenalin. With a head shot you shut them off like a switch. High neck shots accomplish the same thing in my experience.

[50cal Smokepole]

Not if you want a trophy!
A well placed shot behind the shoulder with a good round (high sectional density, terminal performance, etc.) will often drop a whitetail where they stand. I don't advocate head shots. Too small of a target and too much of a chance of wounding an animal. Save the head shots for small game.