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The problem with all blood work is that it is NOT a true indicator of what is actually going on inside the cell. The body has a very effective system of balancing itself chemically and we have yet to discover a way to really measure what is going on at a cellular level(which is what really matters and where damage occurs.)

For example, the reason why we have such a high incidence of osteoporosis in this country is because we eat a very high protein diet which tends to make the blood too acidic. The body compensates by removing calcium from the bone to buffer the pH of the blood. If you check women with osteoporosis, the blood work for Ca++ would be normal, but all the while damage is occurring.

Our population is horribly deficient in Magnesium and B vitamins due to these nutrients being farmed out of our soil (overuse).
Magnesium is a cofactor in 326 different body processes, as well as detoxification of poisons,pesticides,alcohol,etc.. B vits are used up quickly in stress.

Another thing I've often wondered. If soldiers were given heavy doses of the B vitamins when they are involved in battlefield conditions, would they have the same degree of Post Traumatic Stress Disorder. These symptoms are triggered by an overactive amygdala in the brain. Once the reaction is imprinted with no balance from the frontal cortex (logical cognitive portion of the brain)it is difficult to short circuit.

In both surgery and PTSD, it couldn't hurt to give heavy doses and evaluate the results. The RDA for vitamins is actually the minimum you must take to prevent disease and in no way assists with optimum health. There would be little to no risk.

Another thing, in recent research, high doses of B vits in rats with induced Alzheimer type symptoms, have been shown to “untangle” the damaged proteins and neurons in the brain and restore previous neurological function. Promising? I hope.

Sorry so verbose!