We have no naturalistic explanation for the first living cell, nor are within a billion light years of one. Furthermore, mathematical analyses have demonstrated over and over beyond any reasonable doubt that it could not possibly have come about by purely naturalistic mechanisms. The only other logical possibility is intelligent design.
People like you simply close your eyes and then insist that the world is dark. Your thought process is what is “vacuous.”
I wouldn't expect a mathematical analysis to solve a novel problem in chemistry, but I expect progress by actual chemists to continue.
Are you using light year as a unit of time, or of distance? It's hard to tell from the context.
Are you suggesting that unsolved problems in science should be abandoned? What about unsolved problems in medicine?