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To: Sols

Plus, there isn't any PROOF that Gardisol prevents anything actualy. The study isn't old enough to be conclusive. None of it's virgin test patients are even old enough to develop cervical cancer, and won't be for years to come. Plus with all the check ups they get, they probably never will.


153 posted on 02/06/2007 11:47:17 AM PST by Nathan Zachary
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To: Nathan Zachary

"Plus, there isn't any PROOF that Gardisol prevents anything actualy."

More than for the Salk Polio vaccine was put into widespread use, actually.


156 posted on 02/06/2007 11:48:40 AM PST by MeanWestTexan (Kol Hakavod Lezahal)
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To: Nathan Zachary

You can tell if someone is immune to HPV without them making whoopie, you know. Well you don't know, I guess. Turn of phrase.

They are plenty old to show precancerous symptoms (which do not always lead to cancer, of course, but are something to be looked at).

"Two multicenter Phase III trials (titled FUTURE I and II for Females United to Unilaterally Reduce Endo/Ectocervical Disease) were conducted to further evaluate the safety and efficacy of the quadrivalent HPV vaccine. FUTURE I assessed 5,442 girls and women over a period of 2.4 years. There were no cases of CIN 1, CIN 2/3, AIS in the vaccine recipients, compared to 37 cases in the placebo patients (100, 95% CI 89.5, 100) There were also no cases of genital warts in the vaccine group, compared to 29 cases in the placebo group (100, 95% CI 86.4, 100)

FUTURE II enrolled 12,157 women for a two year period. At follow-up, there were 4 cases of precancerous lesions in the vaccine group, compared to 43 cases in the placebo group (90.7, 95% CI 74.4, 97.6). There was one case of genital warts in the vaccine group, compared to 59 in the placebo group (98.3, 95% CI 90.2, 100). There were no cases of cervical cancer reported."

http://www.medscape.com/viewarticle/549278


168 posted on 02/06/2007 12:01:17 PM PST by Sols
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To: Nathan Zachary
Plus, there isn't any PROOF that Gardisol prevents anything actualy. The study isn't old enough to be conclusive. None of it's virgin test patients are even old enough to develop cervical cancer, and won't be for years to come.

There is proof that it prevents four types of HPV infection, including types which contribute to 70% of cervical cancer cases. There is proof that it prevents precancerous lesions -- there were 136 of those in the placebo group, and four in the test group. That's what, a thirty-four fold reduction? Maybe not perfect, but it's a start. As the prevalence of the targeted HPV types decreases in the population, even that tiny minority in whom the vaccine was not effective will benefit, since the odds of getting the killer variants will decrease.

I'm not sure how much more proof you can get than that, nor how many people should die or undergo costly medical procedures while that proof is being collected.

173 posted on 02/06/2007 12:03:03 PM PST by Caesar Soze
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