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That is why the small states got equal representation in the Senate.

That is why slave states received over-representation by the 3/5 rule.

These were the compromises necessary to get them to join the Union.

However, there was never an intent of having a Union in which a State could simply withdraw from when it felt like it.

It was for this reason that Patrick Henry was against the Constitution,

When Henry talked about consolidated government, he and other Anti-Federalists meant that once Virginia joined the new union, it would cease to be an autonomous political entitity; furthermore, once it entered into such arrangement, it would be legally obligated to remain no matter how oppressive the new government had become. The Articles of Confederation had been a compact that states could voluntarily join and leave if they felt the union was not in its best interest. The Constitution, on the other hand, with its preamble proclaiming 'We the People' to be sovereign, would create a legal entity whose laws would be supreme throughout the land and in which the independence of the states would be drastically curtailed. (James Madison and the Struggle for the Bill of Rights, Richard Labunski, 2006, p.77)

If anyone thought differently, they were simply wrong.