It has been frequently commented that Eastern Woodland Indians have facial feature that are distinctly European.
I wouldn't have any problem with contact, even 2 way contact.
Yes, many of the earliest explorers and fishermen remarked on their stature, lighter skin, blue/green eyes/ strong, straight bones "no rickets" that the Europeans were afflicted with
The Native Americans had a much better diet, got more healthy exercise and plenty of sun - (no dairy, no sugar or white flour (corn meal) only 'wild' meat, no Coca Cola _;o) ,,,no time clocks to punch - and they lived long lives...before the white man. If we paid more attention to eating the foods indigenous to the areas we lived in, got more exercise in the fresh air and sunshine - we would probably be a lot healthier.