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REPORT: HUMAN-TO-HUMAN BIRD FLU SUSPECTED IN INDONESIA
http://www.drudgereport.com ^

Posted on 05/23/2006 4:46:15 PM PDT by utvolsfan13

Seven Indonesian Bird Flu Cases Linked to Patients (Update1) May 23 (Bloomberg) -- All seven people infected with bird flu in a cluster of Indonesian cases can be linked to other patients, according to disease trackers investigating possible human-to-human transmission of the H5N1 virus.

A team of international experts has been unable to find animals that might have infected the people, the World Health Organization said in a statement today. In one case, a 10-year- old boy who caught the virus from his aunt may have passed it to his father, the first time officials have seen evidence of a three-person chain of infection, an agency spokeswoman said. Six of the seven people have died.

Almost all of the 218 cases of H5N1 infections confirmed by the WHO since late 2003 can be traced to direct contact with sick or dead birds. Strong evidence of human-to-human transmission may prompt the global health agency to convene a panel of experts and consider raising the pandemic alert level, said Maria Cheng, an agency spokeswoman.

``Considering the evidence and the size of the cluster, it's a possibility,'' Cheng said in a telephone interview. ``It depends on what we're dealing with in Indonesia. It's an evolving situation.''

The 32-year-old father in the cluster of cases on the island of Sumatra was ``closely involved in caring for his son, and this contact is considered a possible source of infection,'' The WHO said in its statement. Three others, including the sole survivor in the group, spent a night in a ``small'' room with the boy's aunt, who later died and was buried before health officials could conduct tests for the H5N1 virus.

`Directly Linked'

``All confirmed cases in the cluster can be directly linked to close and prolonged exposure to a patient during a phase of severe illness,'' the WHO said.

While investigators have been unable to rule out human-to- human transmission in the Sumatran cluster, they continue to search for other explanations for how the infections arose, the WHO statement said.

Health experts are concerned that if H5N1 gains the ability to spread easily among people, it may set off a lethal global outbreak of flu. While some flu pandemics are relatively mild, the 1918 Spanish flu pandemic killed an estimated 50 million people worldwide.

So far, studies of the Sumatran outbreak and genetic analyses of the virus don't indicate the virus has undergone major changes, Cheng said. Scientists at WHO-affiliated labs in the U.S. and Hong Kong found no evidence that the Indonesian strain of H5N1 has gained genes from pigs or humans that might change its power or spreading ability, WHO said.

Mutations

``These viruses mutate all the time and it's difficult to know what the mutations mean,'' Cheng said.

Health officials earlier found strong evidence of direct human-to-human spread of H5N1 in Thailand in 2004. Scientists reported in the Jan. 27, 2005, issue of the New England Journal of Medicine that the H5N1 virus probably spread from an 11-year- old girl in Thailand to her aunt and mother, killing the mother and daughter. People who had more casual contact with the girl didn't become infected.

In the Sumatran cluster, close, direct contact with a severely ill person was also needed for spread, Cheng said. Preliminary findings from the investigation indicate that the woman who died, considered to be the initial case, was coughing frequently while the three others spent the night in the same room. One of the three, a second brother, is the sole survivor. The other two, her sons, died.

``It looks like the same behavior pattern'' of close contact and caretaking during illness with the bird flu virus, Cheng said. To raise the level of pandemic alert ``it would have to be transmissible from more casual contact.''

General Community

The Indonesian Ministry of Health and international scientists are continuing their investigation to trace the origins of the infections, the WHO said in its statement.

``Priority is now being given to the search for additional cases of influenza-like illness in other family members, close contacts, and the general community,'' the WHO said. ``To date, the investigation has found no evidence of spread within the general community and no evidence that efficient human-to-human transmission has occurred.''


TOPICS: Culture/Society; Foreign Affairs; News/Current Events
KEYWORDS: birdflu
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Linked on drudge.. It wouldn't let me link it directly to the article
1 posted on 05/23/2006 4:46:17 PM PDT by utvolsfan13
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To: utvolsfan13
First?

WE ARE ALL GOING TO DIE!!!!

;)

2 posted on 05/23/2006 4:48:46 PM PDT by kAcknor (Don't flatter yourself.... It is a gun in my pocket.)
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To: utvolsfan13

http://www.bloomberg.com/apps/news?pid=10000080&sid=aWESsJvt6CFE&refer=asia here you go. I guess Bloomberg scooped Drudge by about four days.


3 posted on 05/23/2006 4:49:28 PM PDT by satchmodog9 (Most people stand on the tracks and never even hear the train coming)
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To: kAcknor
``These viruses mutate all the time and it's difficult to know what the mutations mean,'' Cheng said.

My God! An actual statement of fact!

4 posted on 05/23/2006 4:50:04 PM PDT by MarcusTulliusCicero
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To: kAcknor
You did it wrong. See Laz for lessons :-)
5 posted on 05/23/2006 4:50:23 PM PDT by steveegg (Sen. Ted "Swimmer" Kennedy's vehicles have killed more people than V.P. Dick Cheney's guns)
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To: utvolsfan13

Quarantine this area now.


6 posted on 05/23/2006 4:50:37 PM PDT by pax_et_bonum (Why did the three wise men have ashes in their beards? Because they had just come from afar.)
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To: utvolsfan13

SIx out of seven died. The enviros will be getting their hopes up again.


7 posted on 05/23/2006 4:56:48 PM PDT by sphinx
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To: utvolsfan13
The fatality rate is so scary: 6 of 7 dead. I read somewhere that the virus will have to get a bit milder to be really dangerous. If you kill 80-100% on contact, the flu will be limited to pockets of disease--like Ebola. Ebola kills so efficiently that it doesn't spread very effectively.

The Spanish Flu killed 20-30% of those who contracted it. Also, it killed younger people more than older. The young people's strong immune system went totally overboard and killed them in one day a lot of the time.

8 posted on 05/23/2006 5:04:37 PM PDT by DJtex
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To: Judith Anne; Termite_Commander; blam; Oorang; Dog Gone; RONALDUS MAXIMUS

Okay, little list. A new article.


9 posted on 05/23/2006 5:13:10 PM PDT by little jeremiah
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To: DJtex
The case fatality rate for the Indonesian strain stands at 88%, according to WHO. Of course, that is a small sample. However, this Indonesian strain seems to be a particularly virulent strain. Many of those who died had intensive hospital care and still didn't make it.

This is not a good sign. Hopefully, the antivirals the US is immediately sending from our stockpile will contain it and it will burn out.

10 posted on 05/23/2006 5:16:13 PM PDT by Gritty (If H5N1 goes human-to-human, none of us know what the human mortality would be- Dr M Osterholm)
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To: DJtex

All the figures I've read of the mortality rate of the 1918 flu are much lower, around 5%. Regular garden variety flu is much less than that, and kills about 36,000 people in the US every year. A flu which is transmitted easily and kills even 5% will kill a tremendous number of people. Small pox is around 30%.

Gotta read that book "The Great Flu" or whatever it's called. If anyone knows the actual title can you ping me?


11 posted on 05/23/2006 5:18:49 PM PDT by little jeremiah
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To: Gritty
...case fatality rate for the Indonesian strain stands at 88%

Actually, those above figures were for 2006 only. The overall Indonesian case fatality rate for 2005-06 is 78.6%, 33deaths/42cases (not a lot more hopeful).

The numbers apparently don't contain some of the latest deaths as WHO is very slow.

12 posted on 05/23/2006 5:24:06 PM PDT by Gritty (It’s not that high-tech medicine doesn’t exist, but that it won’t be available – Dr M Osterholm)
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To: kAcknor

First with the other alternative to same thing:WE ARE DOOMED!


13 posted on 05/23/2006 5:26:02 PM PDT by lexington minuteman 1775
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To: kAcknor

Impossible.. Algore says global warming will get us first.


14 posted on 05/23/2006 5:27:27 PM PDT by Screamname (By God, pray for me, someone help me please! Hillary is my Senator! HELP MEEE!)
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To: Smokin' Joe

Didn't know if you had seen this.


15 posted on 05/23/2006 5:28:50 PM PDT by Judith Anne (Thank you St. Jude for favors granted.)
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To: utvolsfan13

Guess it's time to dig out my old copy of "The Stand"...


16 posted on 05/23/2006 5:31:21 PM PDT by apillar
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To: utvolsfan13
"So far, studies of the Sumatran outbreak and genetic analyses of the virus don't indicate the virus has undergone major changes, Cheng said. Scientists at WHO-affiliated labs in the U.S. and Hong Kong found no evidence that the Indonesian strain of H5N1 has gained genes from pigs or humans that might change its power or spreading ability, WHO said."

Here's the defining statement in this article. This is similar to people getting it from close (handling) contact with chicken/birds. I don't think we've seen a 'shift' yet.

Some other facts: The 2005 mortality for Bird Flu was 55%, for 2006 (YTD) it is 70+%. This data is from people who were confirmed to have had H5N1 flu.

17 posted on 05/23/2006 5:32:22 PM PDT by blam
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To: Gritty
The case fatality rate for the Indonesian strain stands at 88%, according to WHO. Of course, that is a small sample.

There are flaws in the statistical method.

If a person catches this flu, doesn't go to the doctor and does recover, its not noted.

People who die from it are.

18 posted on 05/23/2006 5:32:58 PM PDT by Doe Eyes
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Comment #19 Removed by Moderator

To: Screamname
"Impossible.. Algore says global warming will get us first."

Don't forget the asteroid impact forecasted for Thursday, 5-25-2006.

20 posted on 05/23/2006 5:34:24 PM PDT by blam
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