You have got to be joking....the politicans would be politicans....its the American people who would demand the government go Roman on someone.
Moreover, it would happen before anyone knew what happened.
Here's a guess at what the media (and the rest of us) would see:
-Communications from Tel Aviv cease abruptly
-A few minutes later, indications show that a nuclear weapon went off in the city center
-15 to 20 minutes later, data from USGS website show unusual seismic events in Iran.
-President and some Air Force generals explain via a television broadcast a few hours later that radar detected an unexpected suborbital launch in Iran. Once it was clear that a nuclear attack had occured, certain treaty obligations were invoked and the aggressor was punished in such a way that it will no longer pose a threat.