Why should someone be in trouble? Throughout history, researchers HAVE to use human beings in drug trials. If they didn't there would be no polio vaccine or any of the drugs that are used to successfully treat cancer. I think it's scary that this case is getting a lot of attention. Now researchers are put on the defensive - something that will possibly prevent future drug "cure-alls".
It sounds like the drug should have been eliminated for consideration in the animal trials. If you do shoddy work in the animal trials and then move on to human trials when there's good reason to expect adverse effects, that's unethical.