This is a complete no brainer. People don't eat, rest, exercise properly, abuse the creation, and then blame the designer for faulty design. How stupid is that?
The same is true of the human spinal column; it is not fully adapted for upright stance, but can no longer support our frames in a horizontal stance. It is literally a structure in transition. It is because of this "neither-here-nor-there" situation that back problems are so prevalent.
Shall we discuss the human knee, or the eye, or any of the other ad hoc features of human anatomy?
Ok. You absolve the designer of blame for our Rube Goldberg digestive tracts because people don't care for them properly.
What about the balance of my list?