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To: AndrewC
...protamine-like sequences and are of histone domains.

My point exactly. Protamines and histones are obviously related, as you can see from the sequence fragments here. In addition, we know that protamines can serve as functional alternatives to histones - Nature, 403, 261-263(2000). Or are you still chasing poor Fred and his absolute, 100%, no-way-in-hell impossibility theory?

Sorry, Hoyle loses.

288 posted on 01/29/2006 9:17:44 PM PST by Senator Bedfellow
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To: Senator Bedfellow
My point exactly.

Nope! This was your point exactly ---homologs such as the protamines may well have served some entirely different function before doing what histones do now. A minor change to that homolog, and presto - histones

Plus, this

AKAKKSPRKKAAVKKSTKSKAKKPKSPKKKAAKKTARKSPKKKARKSPKKKAAKKSKK

is not obviously related to this

VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG

Especially with a minor change qualification. Evidence follows.

Sequence 1: lcl|seq_1
Length = 58

Sequence 2: lcl|seq_2
Length = 82


No significant similarity was found

CPU time:     0.01 user secs.	    0.00 sys. secs	    0.01 total secs.

Lambda     K      H
   0.290    0.103    0.249 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 29
Number of extensions: 23
Number of sequences better than 10.0: 0
Number of HSP's gapped: 0
Number of HSP's successfully gapped: 0
Length of query: 58
Length of database: 1,122,496,163
Length adjustment: 33
Effective length of query: 25
Effective length of database: 1,122,496,130
Effective search space: 28062403250
Effective search space used: 28062403250
Neighboring words threshold: 9
X1: 17 ( 7.1 bits)
X2: 129 (49.7 bits)
X3: 129 (49.7 bits)
S1: 44 (21.7 bits)
S2: 70 (31.6 bits)

289 posted on 01/29/2006 9:43:07 PM PST by AndrewC (Darwinian logic -- It is just-so if it is just-so)
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