[FreeReign]

My understand is that Mohammad stated that Mecca would never fall. To annihilate it would demonstrate that he was a false prophet.

You're dealing in reason. Their faith is unreasonable.

They'd probably make up something like this;

Mad Mullahs: Ah...the annihilation of Mecca signifies nothin'. It's Mohammad's will to...ah...remodel.

Followers: Oh, okay.

[America's Resolve]

No. The Haj to Mecca is one of the 5 Pillars of Islam. Without it, they don't get to paradise. Hard to make a pilgrimige to a nuclear wasteland.