That's close to 400 years.
After that, the family was on the move for a long time, even to Indianapolis, Indiana.
My Huguenot ancestors came over on a land grant from the king in the late 1800s. They were placed west of the City of Richmond as a barrier between the English and the Indians. I don't live too far from there now.
Of course, I have American Indian ancestors who were here a good while before that. ;-)