Spyaxe is a "RAT", not adware so to speak and not a virus.
It will morph, it will regen, it protects itself from deletion. It will cause pain.
It's the first infection of any sort I've had in 6 years. It withstood every spyware removal program I threw at it, including symantics.
I back up weekly, so I didn't waste a lot of time with it. It's a doozy and hopefully causes someone some jail time.
Try running your removal tools in Safe Mode. If they'r worth anything they will kill it.
Spyware and viruses are two different animals. Generally- viruses are about control and destruction, and spyware is about money; E.G getting ads in your face and tracking your browsing to see what ads are most likely to get you to spend money- and then it puts them in your face.
I haven't fought Spyaxe in particular, but now that it is becoming more widespread- I will 'contaminate' a test unit and play with it.
The #1 'trick' that I know of when removing bugs, trojans and spyware is to shutdown your Restore Program before starting any removals.