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To: Right Wing Professor
...for which we have no scientific evidence

There is no scientific evidence for RNA world. RNA has never been seen evolving into DNA. No naturally occurring RNA molecules have been found that direct the replication of other RNA molecules. It's all supposition.

and no even plausible mechanism for implementing the design (other than 'poof!').

Well, no it would be a force unknown implementing the design. Sort of like how RNA would switch roles with DNA.

The main reason it hydrolyses easily in a lab is the ubiquity of nuclease enzymes - which obviously weren't a problem in prebiotic environments.

The prebiotic envirnoment is still subject to debate. Even without hydrolysis, RNA breaks down from background radiation. Anyway, the lack of enzymes is also a stumbling block. Without protein enzymes, researchers have not been able to produce a duplicate of a RNA template.

139 posted on 11/03/2005 5:04:01 PM PST by Tribune7
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To: Tribune7
There is no scientific evidence for RNA world. RNA has never been seen evolving into DNA.

RNA is transcribed into DNA in every human being every day. RNA hybridizes with DNA, and there is complete compatibility between RNA nucleotides and DNA nucleotides.

No naturally occurring RNA molecules have been found that direct the replication of other RNA molecules.

Wrong, I'm afraid. Very, very wrong.

Performing your original search, RNA-dependent RNA polymerase, in PubMed will retrieve 2020 citations.

Well, no it would be a force unknown implementing the design. Sort of like how RNA would switch roles with DNA.

Happens in every RNA virus.

Even without hydrolysis, RNA breaks down from background radiation.

So does DNA, at essentially the same rate. Photochemically, there's little difference. The big difference between RNA and DNA is the availability of 2',3' cyclic intermediates for RNA hydrolysis

Anyway, the lack of enzymes is also a stumbling block. Without protein enzymes, researchers have not been able to produce a duplicate of a RNA template.

This has not been a good day for you.

143 posted on 11/03/2005 7:34:42 PM PST by Right Wing Professor (If you love peace, prepare for war. If you hate violence, own a gun.)
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