You can't sit around microcalculating what you do based on the category of the storm; through rapid intensification storms can go up 2 to even 3 categories basically instantly (6-18 hours), and there's no place on the planet where that's more likely than around South Florida and the Keys.
The state was sending a National Guard cargo plane to evacuate 22 patients from Key West's hospital to Sebring, near Lake Okeechobee, Florida. Several critically ill patients already had been evacuated to hospitals in Miami.
Thank goodness for Jeb Bush.