Read "Death in the Long Grass". Its a great contemporary hunting book about huntng man-eating lions in Africa. In game parks where they are not hunted, they loose any fear of man and can become maneaters.
Tests have been done on caged coyotes. They took some food item and added something to it that made the coyote who ate it very sick. That coyote would then avoid that food item. But the curious thing is that when then put that coyote in a pen with other coyotes who had never eaten the drugged food, and then presented THOSE coyotes with that food item, they ALL refused it.
Animals can learn, some can learn better than others and in the intelligence area, predators, especially hgiher predators like Cougars, wolves, coyotes, etc are smartest.
After all, aren't humans the greatest predator?
That's pretty cool... so if we passed a few laws that everybody who goes outside has to be covered in DEET, we'd all be safe after a few predators learned some taste aversion! Safe from mosquitoes AND from coyotes! Just kidding, I'd rather we go with the hunting option- much more fun.