Just bugbomb the house. My wife was bitten by one in NC as was a friend. It's really ugly.
i would question that she was bit at night...by a brown recluse. it still could have been a spider that she rolled over on. The Brown recluse wound becomes necrotic whereas other spider bites tend to look mean but no necrosis.
it's not uncommon to wake up in the morning and see a huge red area that looks like an infection with no pain. they run their course over several days.
nick