Notwithstanding that it's a mosque and not a temple you're looking at there...if the national will existed to wipe the Dome of the Rock off the face of the earth, I estimate its lifespan at about ten minutes from the time the decision is made.
However, it would take an event of truly cosmic importance to unify Israel to that degree.
How many 500#ers would it take?
I'm sure that we could get a work party put together.
I'll bring my Sawzall and wrecking bar.
Anyone else?