Likely, it's either dead or will be renegotiated to accomodate the contintental socialists even more. Frankly, Old Europe is gone anyway--it will be an islamic state in 35 years--so I don't think the costitution means much one way or the other in the long term for old europe.
The plus is that rejection of the constitution means the Brits are much less likely to go for it. So it may prevent the continent from dragging Britain down with it (as well as selected Eastern European countries). Net net, if Britain and Eastern Europe stays (or becomes) a bastion of freedom near Islamic Old Europe, that is a win for Britain and the world.
Economically, it matters little for the world. Europe is a declining power. The economic focus of the world will increasingly be on India, China, Japan and the US.
The Euro is not dependent on passage.
The constitution has to be ratified unanimously (by all countries) to become effective. So one other possibility is that the French gvt just submits it over and over until they get a yes or, more likely, they just ignore the vote and ratify it in parliament.
All 25 countries must ratify the constitution, not the citizens/subjects of those countries but the countries themseleves. I assume by countries they mean governments.
The vote in France and Brussels is a political gamble, not neccessary for eventual passage of constitution, but a yes vote in France would be used to beat UK and any other resisters into submission. Looks like they will have to try Plan B.
No all 9 countries who have signed on so far signed on did it by referendum, some just did it.