[Paleo Conservative]

The A380 may be most successful, however, as a freighter.

Only for low density and palletized freight. The second main deck floor has weight limits. There will be no front cargo door for oversized cargo. It may be useful for Fedex and UPS, but it won't be useful for high value oversized loads.

[Fred Hayek]

High value oversized loads - Already Airbus is beaten even by Antonov. I have seen some big Antonov freighters fly into MSP. Those big birds have even carried railway locomotives to Australia.