It could be done. Just have to make a drone that can take off and fly in an inert atmosphere with a pressure approximating the Earth's at 100,000 feet altitude.
A helium filled balloon using metallic fabric could work.
Make it like a dirigible with a camera and sensor pod hanging on the bottom. Inflate it, and when the gas inside has enough lifting power a lead weight or electro magnet releases sending the floating probe skyward to drift with the wind.