The new 5.7 liter Hemi V-8 is a much more fuel efficient engine than you think. In most applications, the engine utilizes MDS (multi-displacement system) that shuts off 4 of 8 cylinders when cruising to conserve fuel.
A Chrysler 300C, Dodge Magnum, Dodge Durango or Jeep Grand Cherokee with the 5.7 liter Hemi V-8 get fuel economy near that of a large 6 cylinder engine.
I have a new Honda Odyssey that shuts off three of the cylinders when cruising. So far in town I'm getting 22 mpg in city driving which is pretty good for the large family truckster. Haven't tried it on the highway, yet. The shutting on/off of the cylinders is seamless too, with no associated noise, vibration or surge.
I had am '82 Plymouth Horizen that shut off 2 out of 4 cylinders all the time.