I am not saying legalize those things. What I am saying, however, is that the Founding Fathers intended all those things to be State issues since they aren't specific powers given in the Constitution to the Federal gov't.
The 14th amendment had a lot to do with it. Much of the federal Bill of Rights now applies to the states such that a ruling by the USSC affects all states.
For example, if the USSC declares that abortion, or sodomy, or nude dancing, or pornography is a constitutionally protected right, the 14th amendment applies that ruling to all state laws, not just federal laws (as the Founding Fathers intended).
The only part of that list where Congress (not the USSC) stepped in was recreational and prescription drugs (alcohol is regulated at the state level). If this country wishes recreational and prescription drugs to be regulated at the state level, then I would suggest a federal amendment, similar in wording to the 21st amendment, taking that power away from the federal government.