Bear in mind that all of those rights are qualified in the Bill of Rights and in the 14th Amendment.
No person shall [...] be deprived of life, liberty, or property, without due process of law; nor shall private property be taken for public use, without just compensation. - 5th Amendment
No State shall [...] deprive any person of life, liberty, or property, without due process of law; [...] - 14th Amendment
That's not to say that I don't agree that the Commerce Clause has been abused beyond all recognition. I simply think it's important to understand that the Constitution qualifies many of the rights that it enumerates.
Bear in mind that all of those rights are qualified in the Bill of Rights and in the 14th Amendment.
Prohibitions are not reasonable regulations, using due process of law. -- They are banns on some guns, & 'wars' on drugs, and attempts to legislate morality.