Seems the participants in this study were over the age of 70, and already had succeptibility to heart trouble.
My question is: Why were these facts left out of the original story?
The ambiguities of a particular drugs effect upon body systems must be weighed in any given patient circumstance. Aspirin is also a COX inhibitor, yet it is used extensively to "prevent" heart attacks. Theoreticaly there are anticoagulant effects of COX1 inhibitors, and pro-coagulant effects from COX2 inhibitor. Although minor, they show up when examining large groups of people. It is important not to ban a drug for this, but that the physician keep this in mind when selecting a COX inhibitor for a patient in need.
And by the way, the main reason drug costs are so high is that they are out of the capitalist system. The answer is to put (almost) all non-controlled substances OVER THE COUNTER... as in most other countries. Doctors would still be needed, and the prices of the drugs (d/t competition) would plummet.
I can't answer your question about the tests. However, my wife and some of her co-workers aged in 40's & 50's were showing heart problem symptoms on Vioxx.